Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capac...
Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
About this item
Full title
Author / Creator
Meyer zu Natrup, Christian , Tscherne, Alina , Dahlke, Christine , Ciurkiewicz, Malgorzata , Shin, Dai-Lun , Fathi, Anahita , Rohde, Cornelius , Kalodimou, Georgia , Halwe, Sandro , Limpinsel, Leonard , Schwarz, Jan H. , Klug, Martha , Esen, Meral , Schneiderhan-Marra, Nicole , Dulovic, Alex , Kupke, Alexandra , Brosinski, Katrin , Clever, Sabrina , Schünemann, Lisa-Marie , Beythien, Georg , Armando, Federico , Mayer, Leonie , Weskamm, Marie L. , Jany, Sylvia , Freudenstein, Astrid , Tuchel, Tamara , Baumgärtner, Wolfgang , Kremsner, Peter , Fendel, Rolf , Addo, Marylyn M. , Becker, Stephan , Sutter, Gerd and Volz, Asisa
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
The SARS-CoV-2 spike (S) glycoprotein is synthesized as a large precursor protein and must be activated by proteolytic cleavage into S1 and S2. A recombinant modified vaccinia virus Ankara (MVA) expressing native, full-length S protein (MVA-SARS-2-S) is currently under investigation as a candidate vaccine in phase I clinical studies. Initial result...
Alternative Titles
Full title
Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
Authors, Artists and Contributors
Author / Creator
Tscherne, Alina
Dahlke, Christine
Ciurkiewicz, Malgorzata
Shin, Dai-Lun
Fathi, Anahita
Rohde, Cornelius
Kalodimou, Georgia
Halwe, Sandro
Limpinsel, Leonard
Schwarz, Jan H.
Klug, Martha
Esen, Meral
Schneiderhan-Marra, Nicole
Dulovic, Alex
Kupke, Alexandra
Brosinski, Katrin
Clever, Sabrina
Schünemann, Lisa-Marie
Beythien, Georg
Armando, Federico
Mayer, Leonie
Weskamm, Marie L.
Jany, Sylvia
Freudenstein, Astrid
Tuchel, Tamara
Baumgärtner, Wolfgang
Kremsner, Peter
Fendel, Rolf
Addo, Marylyn M.
Becker, Stephan
Sutter, Gerd
Volz, Asisa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c3dacfdcee5044c4a6d220158af4b33c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3dacfdcee5044c4a6d220158af4b33c
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI159895
