Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues...
Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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X-chromosome inactivation (XCI) silences one X in female cells to balance sex-differences in X-dosage. A subset of X-linked genes escape XCI, but the extent to which this phenomenon occurs and how it varies across tissues and in a population is as yet unclear. To characterize incidence and variability of escape across individuals and tissues, we co...
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Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
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TN_cdi_doaj_primary_oai_doaj_org_article_c3e0845ba9914d3a8b2f1d204f9deff8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3e0845ba9914d3a8b2f1d204f9deff8
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010556
