Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation
Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation
About this item
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Author / Creator
Publisher
United States: American Chemical Society
Journal title
Language
English
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Publication information
Publisher
United States: American Chemical Society
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Scope and Contents
Contents
Radiotherapy is commonly used to treat cancer, and localized energy deposited by radiotherapy has the potential to chemically uncage prodrugs; however, it has been challenging to demonstrate prodrug activation that is both sustained in vivo and truly localized to tumors without affecting off-target tissues. To address this, we developed a series of...
Alternative Titles
Full title
Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c3f80e25bbe34e328ba277b41fad204a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3f80e25bbe34e328ba277b41fad204a
Other Identifiers
ISSN
2374-7943
E-ISSN
2374-7951
DOI
10.1021/acscentsci.4c00354
