IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Genetic evolution that occurs during cancer progression enables tumour heterogeneity, thereby fostering tumour adaptation, therapeutic resistance and metastatic potential. Immune responses are known to select (immunoedit) tumour cells displaying immunoevasive properties. Here we address the role of IFN-γ in mediating the immunoediting process. We o...
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Full title
IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting
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TN_cdi_doaj_primary_oai_doaj_org_article_c3f98c477bbd4b9ea70b9c3d2946b093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c3f98c477bbd4b9ea70b9c3d2946b093
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms14607
