Combining genomic analyses with tumour-derived slice cultures for the characterization of an EGFR-ac...
Combining genomic analyses with tumour-derived slice cultures for the characterization of an EGFR-activating kinase mutation in a case of glioblastoma
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Publisher
England: BioMed Central
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Language
English
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England: BioMed Central
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Contents
Epidermal growth factor receptor (EGFR) gene alterations and amplification are frequently reported in cases of glioblastoma (GBM). However, EGFR-activating mutations that confer proven sensitivity to tyrosine kinase inhibitors (TKIs) in lung cancer have not yet been reported in GBM.
Using next-generation sequencing, array comparative genomic hyb...
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Full title
Combining genomic analyses with tumour-derived slice cultures for the characterization of an EGFR-activating kinase mutation in a case of glioblastoma
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TN_cdi_doaj_primary_oai_doaj_org_article_c42544280ea24c4989f1bf439bca016f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c42544280ea24c4989f1bf439bca016f
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/s12885-018-4873-9
