Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues
Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
In prostate cancer, normal citrate-producing glandular secretory epithelial cells undergo a metabolic transformation to malignant citrate-oxidizing cells. m-Aconitase is the critical step involved in this altered citrate metabolism that is essential to prostate malignancy. The limiting m-aconitase activity in prostate epithelial cells could be the...
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Full title
Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues
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TN_cdi_doaj_primary_oai_doaj_org_article_c43c9c6deddf45da8f2fe2d7be7f16d1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c43c9c6deddf45da8f2fe2d7be7f16d1
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-5-14
