CD8+ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune e...
CD8+ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The autoimmune immunopathology occurring in multiple sclerosis (MS) is sustained by myelin-specific and -nonspecific CD8
+
T cells. We have previously shown that, in MS, activated T cells undergoing apoptosis induce a CD8
+
T cell response directed against antigens that are unveiled during the apoptotic process, namely caspase-cleaved s...
Alternative Titles
Full title
CD8+ T cells specific for cryptic apoptosis-associated epitopes exacerbate experimental autoimmune encephalomyelitis
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TN_cdi_doaj_primary_oai_doaj_org_article_c47535d4ee694f92a5709e815109f84d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c47535d4ee694f92a5709e815109f84d
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-04310-6
