Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment
Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne and isotretinoin’s mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin and androgen signaling activate the kinase AKT and mechanistic target of rapamycin complex 1 (mTORC1). A Western diet (hyperglycemic carbohydrates and milk/dair...
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Full title
Acne Transcriptomics: Fundamentals of Acne Pathogenesis and Isotretinoin Treatment
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TN_cdi_doaj_primary_oai_doaj_org_article_c4a63aea164c4ffeba7dcb69cf1171af
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4a63aea164c4ffeba7dcb69cf1171af
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ISSN
2073-4409
E-ISSN
2073-4409
DOI
10.3390/cells12222600
