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Non-canonical transcriptional regulation of the poor prognostic factor UGT2B17 in chronic lymphocyti...

Non-canonical transcriptional regulation of the poor prognostic factor UGT2B17 in chronic lymphocyti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4dc21f5f3f949f4aa203b9c9e894dcd

Non-canonical transcriptional regulation of the poor prognostic factor UGT2B17 in chronic lymphocytic leukemic and normal B cells

About this item

Full title

Non-canonical transcriptional regulation of the poor prognostic factor UGT2B17 in chronic lymphocytic leukemic and normal B cells

Publisher

England: BioMed Central

Journal title

BMC cancer, 2024-04, Vol.24 (1), p.410-410, Article 410

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

High expression of the glycosyltransferase UGT2B17 represents an independent adverse prognostic marker in chronic lymphocytic leukemia (CLL). It also constitutes a predictive marker for therapeutic response and a drug resistance mechanism. The key determinants driving expression of the UGT2B17 gene in normal and leukemic B-cells remain undefined. T...

Alternative Titles

Full title

Non-canonical transcriptional regulation of the poor prognostic factor UGT2B17 in chronic lymphocytic leukemic and normal B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c4dc21f5f3f949f4aa203b9c9e894dcd

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4dc21f5f3f949f4aa203b9c9e894dcd

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-024-12143-7

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