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Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergize...

Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergize...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4e30eaef7d54080a0db2c1628bcebbf

Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Pediatric-type diffuse high-grade glioma (pHGG) is the most frequent malignant brain tumor in children and can be subclassified into multiple entities. Fusion genes activating the MET receptor tyrosine kinase often occur in infant-type hemispheric glioma (IHG) but also in other pHGG and are associated with devastating morbidity and mortality.
To...

Alternative Titles

Full title

Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c4e30eaef7d54080a0db2c1628bcebbf

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c4e30eaef7d54080a0db2c1628bcebbf

Other Identifiers

ISSN

1476-4598

E-ISSN

1476-4598

DOI

10.1186/s12943-024-02027-6

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