Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease
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Author / Creator
Oak, Prajakta , Pritzke, Tina , Thiel, Isabella , Koschlig, Markus , Mous, Daphne S , Windhorst, Anita , Jain, Noopur , Eickelberg, Oliver , Foerster, Kai , Schulze, Andreas , Goepel, Wolfgang , Reicherzer, Tobias , Ehrhardt, Harald , Rottier, Robbert J , Ahnert, Peter , Gortner, Ludwig , Desai, Tushar J and Hilgendorff, Anne
Publisher
London: Nature Publishing Group UK
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English
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Publisher
London: Nature Publishing Group UK
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Contents
Neonatal chronic lung disease (nCLD) affects a significant number of neonates receiving mechanical ventilation with oxygen‐rich gas (MV‐O
2
). Regardless, the primary molecular driver of the disease remains elusive. We discover significant enrichment for SNPs in the PDGF‐Rα gene in preterms with nCLD and directly test the effect of PDGF‐Rα ha...
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Full title
Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease
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TN_cdi_doaj_primary_oai_doaj_org_article_c55476416009460e819c1dbc8a378e98
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c55476416009460e819c1dbc8a378e98
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ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.15252/emmm.201607308
