PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection
PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection
About this item
Full title
Author / Creator
Chen, Shuyuan , Putnik, Rachel , Li, Xi , Diwaker, Alka , Vasconcelos, Marina , Liu, Shuzhen , Gondi, Sudershan , Zhou, Junhui , Guo, Lei , Xu, Lin , Temme, Sebastian , Bersch, Klare , Hyland, Stephen , Yin, Jianyi , Burstein, Ezra , Bahnson, Brian J. , Gildersleeve, Jeffrey C. , Grimes, Catherine Leimkuhler and Reinecker, Hans-Christian
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Peptidoglycan recognition proteins (PGLYRPs) are implicated in the control of the intestinal microbiota; however, molecular requirements for peptidoglycan (PGN) binding and receptor signaling mechanisms remain poorly understood. Here we show that PGLYRP1 is a receptor for the disaccharide motif of lysine N-acetylglucosamine N-acetylmuramic tripepti...
Alternative Titles
Full title
PGLYRP1-mediated intracellular peptidoglycan detection promotes intestinal mucosal protection
Authors, Artists and Contributors
Author / Creator
Putnik, Rachel
Li, Xi
Diwaker, Alka
Vasconcelos, Marina
Liu, Shuzhen
Gondi, Sudershan
Zhou, Junhui
Guo, Lei
Xu, Lin
Temme, Sebastian
Bersch, Klare
Hyland, Stephen
Yin, Jianyi
Burstein, Ezra
Bahnson, Brian J.
Gildersleeve, Jeffrey C.
Grimes, Catherine Leimkuhler
Reinecker, Hans-Christian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c55d485d50ca4e2d9443ac246cf3a394
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c55d485d50ca4e2d9443ac246cf3a394
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-57126-9
