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Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a...

Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c573300c5eeb4f41a34f190c3a32f7db

Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosis

About this item

Full title

Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosis

Publisher

England: BioMed Central Ltd

Journal title

BMC musculoskeletal disorders, 2017-06, Vol.18 (1), p.267-267, Article 267

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

ONO-5334 is a cathepsin K inhibitor that induced bone mineral density (BMD) gain in a phase II study in postmenopausal osteoporosis patients. Even though the antiresorptive effect could only be monitored in the morning during the study, simulation can allow the antiresorptive effect to be assessed over 24 h, with assessment of the relationship to B...

Alternative Titles

Full title

Antiresorptive effect of a cathepsin K inhibitor ONO-5334 and its relationship to BMD increase in a phase II trial for postmenopausal osteoporosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c573300c5eeb4f41a34f190c3a32f7db

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c573300c5eeb4f41a34f190c3a32f7db

Other Identifiers

ISSN

1471-2474

E-ISSN

1471-2474

DOI

10.1186/s12891-017-1625-y

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