Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and res...
Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and response to MEK inhibitor
About this item
Full title
Author / Creator
Jiang, Chunhui , Kumar, Ashwani , Yu, Ze , Shipman, Tracey , Wang, Yong , McKay, Renee M , Xing, Chao and Le, Lu Q
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
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More information
Scope and Contents
Contents
Neurofibromatosis type 1 (NF1) is one of the most common tumor-predisposing genetic disorders. Neurofibromas are NF1-associated benign tumors. A hallmark feature of neurofibromas is an abundant collagen-rich extracellular matrix (ECM) that constitutes more than 50% of the tumor dry weight. However, little is known about the mechanism underlying ECM...
Alternative Titles
Full title
Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and response to MEK inhibitor
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c58d1cf601994e0eb228352447eddcec
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c58d1cf601994e0eb228352447eddcec
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI168227
