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Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-...

Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c5c102a1438e4861a3458b1c01a76240

Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-associated neutrophil heterogeneity and establishes a VEGFA+ neutrophil prognostic model

About this item

Full title

Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-associated neutrophil heterogeneity and establishes a VEGFA+ neutrophil prognostic model

Publisher

England: BioMed Central Ltd

Journal title

Biology direct, 2025-04, Vol.20 (1), p.45-22, Article 45

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Neutrophils play a key role in the tumor microenvironment (TME); however, their functions in glioblastoma (GBM) are overlooked and insufficiently studied. A detailed analysis of GBM-associated neutrophil (GBMAN) subpopulations may offer new insights and opportunities for GBM immunotherapy.
We analyzed single-cell RNA sequencing (scRNA-seq) data...

Alternative Titles

Full title

Large-scale bulk and single-cell RNA sequencing combined with machine learning reveals glioblastoma-associated neutrophil heterogeneity and establishes a VEGFA+ neutrophil prognostic model

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c5c102a1438e4861a3458b1c01a76240

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c5c102a1438e4861a3458b1c01a76240

Other Identifiers

ISSN

1745-6150

E-ISSN

1745-6150

DOI

10.1186/s13062-025-00640-z

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