Ectopic FOXP3 Expression in Combination with TGF-β1 and IL-2 Stimulation Generates Limited Suppressi...
Ectopic FOXP3 Expression in Combination with TGF-β1 and IL-2 Stimulation Generates Limited Suppressive Function in Human Primary Activated Thymocytes Ex Vivo
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Regulatory T cells (Tregs), which are characterized by the expression of the transcription factor forkhead box P3 (FOXP3), are the main immune cells that induce tolerance and are regulators of immune homeostasis. Natural Treg cells (nTregs), described as CD4+CD25+FOXP3+, are generated in the thymus via activation and cytokine signaling. Transformin...
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Full title
Ectopic FOXP3 Expression in Combination with TGF-β1 and IL-2 Stimulation Generates Limited Suppressive Function in Human Primary Activated Thymocytes Ex Vivo
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TN_cdi_doaj_primary_oai_doaj_org_article_c60ae1c53ea44599b9d312c68b0b8225
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c60ae1c53ea44599b9d312c68b0b8225
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ISSN
2227-9059
E-ISSN
2227-9059
DOI
10.3390/biomedicines9050461
