De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode...
De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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England: eLife Sciences Publications Ltd
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Contents
ATP-binding cassette (ABC) transporters constitute the largest family of primary active transporters involved in a multitude of physiological processes and human diseases. Despite considerable efforts, it remains unclear how ABC transporters harness the chemical energy of ATP to drive substrate transport across cell membranes. Here, by random nonst...
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Full title
De novo macrocyclic peptides dissect energy coupling of a heterodimeric ABC transporter by multimode allosteric inhibition
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TN_cdi_doaj_primary_oai_doaj_org_article_c60fc880ff0141849e077e85aa6c65b3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c60fc880ff0141849e077e85aa6c65b3
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.67732
