Tonabersat enhances temozolomide‐mediated cytotoxicity in glioblastoma by disrupting intercellular c...
Tonabersat enhances temozolomide‐mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition
About this item
Full title
Author / Creator
Schmidt, Elena N. C. , Evert, Bernd O. , Pregler, Barbara E. F. , Melhem, Ahmad , Hsieh, Meng‐Chun , Raspe, Markus , Strobel, Hannah , Roos, Julian , Pietsch, Torsten , Schuss, Patrick , Fischer‐Posovszky, Pamela , Westhoff, Mike‐Andrew , Hölzel, Michael , Herrlinger, Ulrich , Vatter, Hartmut , Waha, Andreas , Schneider, Matthias and Potthoff, Anna‐Laura
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
More information
Scope and Contents
Contents
Glioblastoma cells rely on connexin 43 (Cx43)‐based gap junctions (GJs) for intercellular communication, enabling them to integrate into a widely branched malignant network. Although there are promising prospects for new targeted therapies, the lack of clinically feasible GJ inhibitors has impeded their adoption in clinical practice. In the present...
Alternative Titles
Full title
Tonabersat enhances temozolomide‐mediated cytotoxicity in glioblastoma by disrupting intercellular connectivity through connexin 43 inhibition
Authors, Artists and Contributors
Author / Creator
Evert, Bernd O.
Pregler, Barbara E. F.
Melhem, Ahmad
Hsieh, Meng‐Chun
Raspe, Markus
Strobel, Hannah
Roos, Julian
Pietsch, Torsten
Schuss, Patrick
Fischer‐Posovszky, Pamela
Westhoff, Mike‐Andrew
Hölzel, Michael
Herrlinger, Ulrich
Vatter, Hartmut
Waha, Andreas
Schneider, Matthias
Potthoff, Anna‐Laura
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c61c3785eee045e5bdb3424b2f51c537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c61c3785eee045e5bdb3424b2f51c537
Other Identifiers
ISSN
1574-7891,1878-0261
E-ISSN
1878-0261
DOI
10.1002/1878-0261.13786
