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Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c655891b73d54aeb8adf1a017f3f60af

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

About this item

Full title

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2018-03, Vol.9 (1), p.1029-12, Article 1029

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Vesicular stomatitis virus (VSV) is an oncolytic rhabdovirus and its glycoprotein G is widely used to pseudotype other viruses for gene therapy. Low-density lipoprotein receptor (LDL-R) serves as a major entry receptor for VSV. Here we report two crystal structures of VSV G in complex with two distinct cysteine-rich domains (CR2 and CR3) of LDL-R,...

Alternative Titles

Full title

Structural basis for the recognition of LDL-receptor family members by VSV glycoprotein

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c655891b73d54aeb8adf1a017f3f60af

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c655891b73d54aeb8adf1a017f3f60af

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-018-03432-4

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