Mitochondrial Ca²⁺ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4...
Mitochondrial Ca²⁺ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
IL-6 plays an important role in determining the fate of effector CD4 cells and the cytokines that these cells produce. Here we identify a novel molecular mechanism by which IL-6 regulates CD4 cell effector function. We show that IL-6-dependent signal facilitates the formation of mitochondrial respiratory chain supercomplexes to sustain high mitocho...
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Full title
Mitochondrial Ca²⁺ and membrane potential, an alternative pathway for Interleukin 6 to regulate CD4 cell effector function
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TN_cdi_doaj_primary_oai_doaj_org_article_c65fbc73b4a04bbea1471bbd828c20b1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c65fbc73b4a04bbea1471bbd828c20b1
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.06376
