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G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery

G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c65fe5256d1847518e22a73b617bb91a

G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery

About this item

Full title

G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery

Publisher

London: Nature Publishing Group UK

Journal title

Signal transduction and targeted therapy, 2024-04, Vol.9 (1), p.88-43, Article 88

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

G protein-coupled receptors (GPCRs), the largest family of human membrane proteins and an important class of drug targets, play a role in maintaining numerous physiological processes. Agonist or antagonist, orthosteric effects or allosteric effects, and biased signaling or balanced signaling, characterize the complexity of GPCR dynamic features. In...

Alternative Titles

Full title

G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c65fe5256d1847518e22a73b617bb91a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c65fe5256d1847518e22a73b617bb91a

Other Identifiers

ISSN

2059-3635,2095-9907

E-ISSN

2059-3635

DOI

10.1038/s41392-024-01803-6

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