G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery
G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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G protein-coupled receptors (GPCRs), the largest family of human membrane proteins and an important class of drug targets, play a role in maintaining numerous physiological processes. Agonist or antagonist, orthosteric effects or allosteric effects, and biased signaling or balanced signaling, characterize the complexity of GPCR dynamic features. In...
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G protein-coupled receptors (GPCRs): advances in structures, mechanisms and drug discovery
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TN_cdi_doaj_primary_oai_doaj_org_article_c65fe5256d1847518e22a73b617bb91a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c65fe5256d1847518e22a73b617bb91a
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ISSN
2059-3635,2095-9907
E-ISSN
2059-3635
DOI
10.1038/s41392-024-01803-6