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A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective int...

A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective int...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c684e2cdb0ba43a69d9c0fdf51449845

A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates

About this item

Full title

A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-04, Vol.14 (1), p.1998-1998, Article 1998

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Engrailed2 (En2) is a transcription factor that transfers from cell to cell through unconventional pathways. The poorly understood internalization mechanism of this cationic protein is proposed to require an initial interaction with cell-surface glycosaminoglycans (GAGs). To decipher the role of GAGs in En2 internalization, we have quantified the e...

Alternative Titles

Full title

A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c684e2cdb0ba43a69d9c0fdf51449845

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c684e2cdb0ba43a69d9c0fdf51449845

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-37757-6

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