Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple spec...
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Microcephaly is a cortical malformation disorder characterized by an abnormally small brain. Recent studies have revealed severe cases of microcephaly resulting from human mutations in the
NDE1
gene, which is involved in the regulation of cytoplasmic dynein. Here using
in utero
electroporation of NDE1 short hairpin RNA (shRNA) in embryo...
Alternative Titles
Full title
Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages
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TN_cdi_doaj_primary_oai_doaj_org_article_c687288b476a44bbbdc01ae2166912dd
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c687288b476a44bbbdc01ae2166912dd
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms12551
