Combination of bacteriophages and vancomycin in a co-delivery hydrogel for localized treatment of fr...
Combination of bacteriophages and vancomycin in a co-delivery hydrogel for localized treatment of fracture-related infections
About this item
Full title
Author / Creator
Chen, Baixing , Ponce Benavente, Luis , Chittò, Marco , Post, Virginia , Constant, Caroline , Zeiter, Stephan , Nylund, Pamela , D’Este, Matteo , González Moreno, Mercedes , Trampuz, Andrej , Wagemans, Jeroen , Lavigne, Rob , Onsea, Jolien , Richards, R. Geoff , Metsemakers, Willem-Jan and Moriarty, T. Fintan
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Fracture-related infections (FRIs), particularly those caused by methicillin-resistant
Staphylococcus aureus
(MRSA), are challenging to treat. This study designed and evaluated a hydrogel loaded with a cocktail of bacteriophages and vancomycin (1.2 mg/mL). The co-delivery hydrogel showed 99.72% reduction in MRSA biofilm in vitro. The hydrogel...
Alternative Titles
Full title
Combination of bacteriophages and vancomycin in a co-delivery hydrogel for localized treatment of fracture-related infections
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c68ff35f89d7425ea2be846a1e1159fc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c68ff35f89d7425ea2be846a1e1159fc
Other Identifiers
ISSN
2055-5008
E-ISSN
2055-5008
DOI
10.1038/s41522-024-00552-2
