Normal tissue radioprotection by amifostine via Warburg-type effects
Normal tissue radioprotection by amifostine via Warburg-type effects
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Author / Creator
Koukourakis, Michael I. , Giatromanolaki, Alexandra , Zois, Christos E. , Kalamida, Dimitra , Pouliliou, Stamatia , Karagounis, Ilias V. , Yeh, Tzu-Lan , Abboud, Martine I. , Claridge, Timothy D. W. , Schofield, Christopher J. , Sivridis, Efthimios , Simopoulos, Costantinos , Tokmakidis, Savvas P. and Harris, Adrian L.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of amifostine on human basal metabolism, mouse liver metabolism and on normal and tumor hepatic cells were studied. Indirect calorimetric canopy tests showed significant reductions in oxygen consumption and of carbon dioxide emission in cancer patients...
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Full title
Normal tissue radioprotection by amifostine via Warburg-type effects
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TN_cdi_doaj_primary_oai_doaj_org_article_c69a6c00eac843e78e856d126f0b005f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c69a6c00eac843e78e856d126f0b005f
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep30986
