ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemne...
ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
p63 is a transcription factor with intrinsic pioneer factor activity and pleiotropic functions. Transforming growth factor β (TGFβ) signaling via activation and cooperative action of canonical, SMAD, and non-canonical, MAP-kinase (MAPK) pathways, elicits both anti- and pro-tumorigenic properties, including cell stemness and invasiveness. TGFβ activ...
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Full title
ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness
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TN_cdi_doaj_primary_oai_doaj_org_article_c69b2398770746ad995d89ef0e1932d9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c69b2398770746ad995d89ef0e1932d9
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-024-01794-5
