Effect of C-terminus Conjugation via Different Conjugation Chemistries on In Vivo Activity of Albumi...
Effect of C-terminus Conjugation via Different Conjugation Chemistries on In Vivo Activity of Albumin-Conjugated Recombinant GLP-1
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Switzerland: MDPI
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English
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Switzerland: MDPI
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Glucagon-like peptide-1 (GLP-1) is a peptide hormone with tremendous therapeutic potential for treating type 2 diabetes mellitus. However, the short half-life of its native form is a significant drawback. We previously prolonged the plasma half-life of GLP-1 via site-specific conjugation of human serum albumin (HSA) at position 16 of recombinant GL...
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Effect of C-terminus Conjugation via Different Conjugation Chemistries on In Vivo Activity of Albumin-Conjugated Recombinant GLP-1
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TN_cdi_doaj_primary_oai_doaj_org_article_c69c61edea3b48d9ab3e7c537a1c0278
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c69c61edea3b48d9ab3e7c537a1c0278
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ISSN
1999-4923
E-ISSN
1999-4923
DOI
10.3390/pharmaceutics13020263
