Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression Se...
Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
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Author / Creator
Colin Valet , Mélia Magnen , Longhui Qiu , Simon J. Cleary , Kristin M. Wang , Serena Ranucci , Elodie Grockowiak , Rafik Boudra , Catharina Conrad , Yurim Seo , Daniel R. Calabrese , John R. Greenland , Andrew D. Leavitt , Emmanuelle Passegué , Simón Méndez-Ferrer , Filip K. Swirski and Mark R. Looney
Publisher
American Society for Clinical Investigation
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Language
English
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Publisher
American Society for Clinical Investigation
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Contents
Platelets have a wide range of functions including critical roles in hemostasis, thrombosis, and immunity. We hypothesized that during acute inflammation, such as in life-threatening sepsis, there are fundamental changes in the sites of platelet production and phenotypes of resultant platelets. Here, we showed during sepsis that the spleen was a ma...
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Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression Sepsis promotes splenic production of a protective platelet pool with high CD40 ligand expression
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TN_cdi_doaj_primary_oai_doaj_org_article_c6be936c86a64996bba945d179a280f3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c6be936c86a64996bba945d179a280f3
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E-ISSN
1558-8238
