CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function
CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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MicroRNAs (miRNAs) are important regulators of diverse physiological and pathophysiological processes. MiRNA families and clusters are two key features in miRNA biology. Here we explore the use of CRISPR/Cas9 as a powerful tool to delineate the function and regulation of miRNA families and clusters. We focused on four miRNA clusters composed of miR...
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CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function
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TN_cdi_doaj_primary_oai_doaj_org_article_c6f1f4ed873b4bfc9c27edba831e3e8f
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c6f1f4ed873b4bfc9c27edba831e3e8f
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-09268-0
