Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in m...
Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality
About this item
Full title
Author / Creator
Sabharwal, Ankit , Wishman, Mark D , Cervera, Roberto Lopez , Serres, MaKayla R , Anderson, Jennifer L , Holmberg, Shannon R , Kar, Bibekananda , Treichel, Anthony J , Ichino, Noriko , Liu, Weibin , Yang, Jingchun , Ding, Yonghe , Deng, Yun , Lacey, Jean M , Laxen, William J , Loken, Perry R , Oglesbee, Devin , Farber, Steven A , Clark, Karl J , Xu, Xiaolei and Ekker, Stephen C
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
Subjects
More information
Scope and Contents
Contents
The clinical and largely unpredictable heterogeneity of phenotypes in patients with mitochondrial disorders demonstrates the ongoing challenges in the understanding of this semi-autonomous organelle in biology and disease. Previously, we used the gene-breaking transposon to create 1200 transgenic zebrafish strains tagging protein-coding genes (Ichi...
Alternative Titles
Full title
Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality
Authors, Artists and Contributors
Author / Creator
Wishman, Mark D
Cervera, Roberto Lopez
Serres, MaKayla R
Anderson, Jennifer L
Holmberg, Shannon R
Kar, Bibekananda
Treichel, Anthony J
Ichino, Noriko
Liu, Weibin
Yang, Jingchun
Ding, Yonghe
Deng, Yun
Lacey, Jean M
Laxen, William J
Loken, Perry R
Oglesbee, Devin
Farber, Steven A
Clark, Karl J
Xu, Xiaolei
Ekker, Stephen C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c6f4d43f2d7246b09a3bf4b4734cee47
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c6f4d43f2d7246b09a3bf4b4734cee47
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.65488
