p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy
p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy
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Publisher
England: The Company of Biologists Ltd
Journal title
Language
English
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Publisher
England: The Company of Biologists Ltd
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Contents
Facioscapulohumeral muscular dystrophy (FSHD) is a genetically dominant myopathy caused by mutations that disrupt repression of the normally silent
gene, which encodes a transcription factor that has been shown to interfere with myogenesis when misexpressed at very low levels in myoblasts and to cause cell death when overexpressed at high levels...
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Full title
p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy
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TN_cdi_doaj_primary_oai_doaj_org_article_c6f8f8e493e24d9098043d936bb0bb26
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c6f8f8e493e24d9098043d936bb0bb26
Other Identifiers
ISSN
1754-8403
E-ISSN
1754-8411
DOI
10.1242/dmm.030064
