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High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeli...

High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeli...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7121fae9196446f87e88d0aaf778d3a

High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling

About this item

Full title

High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling

Publisher

Hoboken, USA: John Wiley & Sons, Inc

Journal title

Stem cells translational medicine, 2021-07, Vol.10 (7), p.1063-1080

Language

English

Formats

Publication information

Publisher

Hoboken, USA: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

To harness the full potential of human pluripotent stem cells (hPSCs) we combined instrumented stirred tank bioreactor (STBR) technology with the power of in silico process modeling to overcome substantial, hPSC‐specific hurdles toward their mass production. Perfused suspension culture (3D) of matrix‐free hPSC aggregates in STBRs was applied to ide...

Alternative Titles

Full title

High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c7121fae9196446f87e88d0aaf778d3a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7121fae9196446f87e88d0aaf778d3a

Other Identifiers

ISSN

2157-6564

E-ISSN

2157-6580

DOI

10.1002/sctm.20-0453

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