High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeli...
High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling
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Publisher
Hoboken, USA: John Wiley & Sons, Inc
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Language
English
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Publisher
Hoboken, USA: John Wiley & Sons, Inc
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Contents
To harness the full potential of human pluripotent stem cells (hPSCs) we combined instrumented stirred tank bioreactor (STBR) technology with the power of in silico process modeling to overcome substantial, hPSC‐specific hurdles toward their mass production. Perfused suspension culture (3D) of matrix‐free hPSC aggregates in STBRs was applied to ide...
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High density bioprocessing of human pluripotent stem cells by metabolic control and in silico modeling
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TN_cdi_doaj_primary_oai_doaj_org_article_c7121fae9196446f87e88d0aaf778d3a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7121fae9196446f87e88d0aaf778d3a
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ISSN
2157-6564
E-ISSN
2157-6580
DOI
10.1002/sctm.20-0453