A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cance...
A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer
About this item
Full title
Author / Creator
Li, Fangfei , Lu, Jun , Liu, Jin , Liang, Chao , Wang, Maolin , Wang, Luyao , Li, Defang , Yao, Houzong , Zhang, Qiulong , Wen, Jia , Zhang, Zong-Kang , Li, Jie , Lv, Quanxia , He, Xiaojuan , Guo, Baosheng , Guan, Daogang , Yu, Yuanyuan , Dang, Lei , Wu, Xiaohao , Li, Yongshu , Chen, Guofen , Jiang, Feng , Sun, Shiguo , Zhang, Bao-Ting , Lu, Aiping and Zhang, Ge
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Paclitaxel (PTX) is among the most commonly used first-line drugs for cancer chemotherapy. However, its poor water solubility and indiscriminate distribution in normal tissues remain clinical challenges. Here we design and synthesize a highly water-soluble nucleolin aptamer-paclitaxel conjugate (NucA-PTX) that selectively delivers PTX to the tumor...
Alternative Titles
Full title
A water-soluble nucleolin aptamer-paclitaxel conjugate for tumor-specific targeting in ovarian cancer
Authors, Artists and Contributors
Author / Creator
Lu, Jun
Liu, Jin
Liang, Chao
Wang, Maolin
Wang, Luyao
Li, Defang
Yao, Houzong
Zhang, Qiulong
Wen, Jia
Zhang, Zong-Kang
Li, Jie
Lv, Quanxia
He, Xiaojuan
Guo, Baosheng
Guan, Daogang
Yu, Yuanyuan
Dang, Lei
Wu, Xiaohao
Li, Yongshu
Chen, Guofen
Jiang, Feng
Sun, Shiguo
Zhang, Bao-Ting
Lu, Aiping
Zhang, Ge
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c74e34d161c444469af0643c90b25955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c74e34d161c444469af0643c90b25955
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-017-01565-6
