Three-dimensional in situ morphometrics of Mycobacterium tuberculosis infection within lesions by op...
Three-dimensional in situ morphometrics of Mycobacterium tuberculosis infection within lesions by optical mesoscopy and novel acid-fast staining
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tuberculosis (TB) preclinical testing relies on in vivo models including the mouse aerosol challenge model. The only method of determining colony morphometrics of TB infection in a tissue in situ is two-dimensional (2D) histopathology. 2D measurements consider heterogeneity within a single observable section but not above and below, which could con...
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Three-dimensional in situ morphometrics of Mycobacterium tuberculosis infection within lesions by optical mesoscopy and novel acid-fast staining
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TN_cdi_doaj_primary_oai_doaj_org_article_c753bc9f75174c4195e6c28918b47a23
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c753bc9f75174c4195e6c28918b47a23
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-78640-4
