DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggre...
DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggressiveness of adrenocortical carcinoma
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Germany: BioMed Central Ltd
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Language
English
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Publisher
Germany: BioMed Central Ltd
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Adrenocortical carcinoma is rare and aggressive endocrine cancer of the adrenal gland. Within adrenocortical carcinoma, a recently described subtype characterized by a CpG island methylator phenotype (CIMP) has been associated with an especially poor prognosis. However, the drivers of CIMP remain unknown. Furthermore, the functional relation betwee...
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DNA hypermethylation driven by DNMT1 and DNMT3A favors tumor immune escape contributing to the aggressiveness of adrenocortical carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_c76717b318a742faa83e043eb3df2200
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c76717b318a742faa83e043eb3df2200
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ISSN
1868-7083,1868-7075
E-ISSN
1868-7083,1868-7075
DOI
10.1186/s13148-023-01534-5
