UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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DNA methylation, repressive histone marks, and PIWI-interacting RNA (piRNA) are essential for the control of retrotransposon silencing in the mammalian germline. However, it remains unknown how these repressive epigenetic pathways crosstalk to ensure retrotransposon silencing in the male germline. Here, we show that UHRF1 is responsible for retrotr...
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UHRF1 suppresses retrotransposons and cooperates with PRMT5 and PIWI proteins in male germ cells
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TN_cdi_doaj_primary_oai_doaj_org_article_c76cb3c76543408a83107042b6b9f1d8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c76cb3c76543408a83107042b6b9f1d8
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-12455-4
