Activation-Free Sulfonyl Fluoride Probes for Fragment Screening
Activation-Free Sulfonyl Fluoride Probes for Fragment Screening
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Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
SuFEx chemistry is based on the unique reactivity of the sulfonyl fluoride group with a range of nucleophiles. Accordingly, sulfonyl fluorides label multiple nucleophilic amino acid residues, making these reagents popular in both chemical biology and medicinal chemistry applications. The reactivity of sulfonyl fluorides nominates this warhead chemo...
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Full title
Activation-Free Sulfonyl Fluoride Probes for Fragment Screening
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TN_cdi_doaj_primary_oai_doaj_org_article_c77c5ffab3114b2793cf463335f0bda9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c77c5ffab3114b2793cf463335f0bda9
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28073042
