Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP)
Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP)
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Muscarinic acetylcholine receptors (mAChR), including M4, draw attention as therapeutic targets for several neurodegenerative diseases including Alzheimer's disease (AD). PET imaging of M4 positive allosteric modulator (PAM) allows qualification of the distribution as well as the expression of this receptor under physiological conditions and thereb...
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Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP)
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TN_cdi_doaj_primary_oai_doaj_org_article_c786115b08284d89ace0c5db57d9ce81
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c786115b08284d89ace0c5db57d9ce81
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ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules28124612
