Repressing miR-23a promotes the transdifferentiation of pancreatic α cells to β cells via negatively...
Repressing miR-23a promotes the transdifferentiation of pancreatic α cells to β cells via negatively regulating the expression of SDF-1α
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United States: Public Library of Science (PLoS)
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English
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United States: Public Library of Science (PLoS)
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Pancreatic β-cell failure is a pathological feature in type 1 diabetes. One promising approach involves inducing transdifferentiation of related pancreatic cell types, specifically α cells that produce glucagon. The chemokine stromal cell-derived factor-1 alpha (SDF-1α) is implicated in pancreatic α-to-β like cell transition. Here, the serum level...
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Full title
Repressing miR-23a promotes the transdifferentiation of pancreatic α cells to β cells via negatively regulating the expression of SDF-1α
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TN_cdi_doaj_primary_oai_doaj_org_article_c7a7d14211e84b548df6726d6a8f3632
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7a7d14211e84b548df6726d6a8f3632
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0299821
