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The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7b746e4219a4abbbee955fa77d3dd3b

The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

About this item

Full title

The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-02, Vol.11 (1), p.2990-2990, Article 2990

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

As the immune system develops with age, children combat infections better. HIV-1, however, targets an activated immune system, potentially rendering children increasingly permissive to HIV-1 infection as they grow. How HIV-1 fitness changes with age in children is unknown. Here, we estimated the within-host basic reproductive ratio,
R
0
,...

Alternative Titles

Full title

The within-host fitness of HIV-1 increases with age in ART-naïve HIV-1 subtype C infected children

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c7b746e4219a4abbbee955fa77d3dd3b

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7b746e4219a4abbbee955fa77d3dd3b

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-82293-2

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