Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity a...
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight
About this item
Full title
Author / Creator
Wu, Fei , Du, Huixun , Overbey, Eliah , Kim, JangKeun , Makhijani, Priya , Martin, Nicolas , Lerner, Chad A. , Nguyen, Khiem , Baechle, Jordan , Valentino, Taylor R. , Fuentealba, Matias , Bartleson, Juliet M. , Halaweh, Heather , Winer, Shawn , Meydan, Cem , Garrett-Bakelman, Francine , Sayed, Nazish , Melov, Simon , Muratani, Masafumi , Gerencser, Akos A. , Kasler, Herbert G. , Beheshti, Afshin , Mason, Christopher E. , Furman, David and Winer, Daniel A.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Microgravity is associated with immunological dysfunction, though the mechanisms are poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear cells (PBMCs) exposed to short term (25 hours) simulated microgravity, we characterize altered genes and pathways at basal and stimulated states with a Toll-like Receptor-7/8...
Alternative Titles
Full title
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight
Authors, Artists and Contributors
Author / Creator
Du, Huixun
Overbey, Eliah
Kim, JangKeun
Makhijani, Priya
Martin, Nicolas
Lerner, Chad A.
Nguyen, Khiem
Baechle, Jordan
Valentino, Taylor R.
Fuentealba, Matias
Bartleson, Juliet M.
Halaweh, Heather
Winer, Shawn
Meydan, Cem
Garrett-Bakelman, Francine
Sayed, Nazish
Melov, Simon
Muratani, Masafumi
Gerencser, Akos A.
Kasler, Herbert G.
Beheshti, Afshin
Mason, Christopher E.
Furman, David
Winer, Daniel A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c7dca3abd2b846df8c5d5d597731d0e9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c7dca3abd2b846df8c5d5d597731d0e9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-42013-y
