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Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation...

Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c833416f75ab4151874dbe6f3b782ba0

Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing

About this item

Full title

Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing

Publisher

United States: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2024-10, Vol.18 (10), p.2541-2553

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Early identification of resistant cancer cells is currently a major challenge, as their expansion leads to refractoriness. To capture the dynamics of these cells, we made a comprehensive analysis of disease progression and treatment response in a chronic lymphocytic leukemia (CLL) patient using a combination of single‐cell and bulk genomic methods....

Alternative Titles

Full title

Unveiling the dynamics and molecular landscape of a rare chronic lymphocytic leukemia subpopulation driving refractoriness: insights from single‐cell RNA sequencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c833416f75ab4151874dbe6f3b782ba0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c833416f75ab4151874dbe6f3b782ba0

Other Identifiers

ISSN

1574-7891,1878-0261

E-ISSN

1878-0261

DOI

10.1002/1878-0261.13663

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