The cell proliferation antigen Ki-67 organises heterochromatin
The cell proliferation antigen Ki-67 organises heterochromatin
About this item
Full title
Author / Creator
Sobecki, Michal , Mrouj, Karim , Camasses, Alain , Parisis, Nikolaos , Nicolas, Emilien , Llères, David , Gerbe, François , Prieto, Susana , Krasinska, Liliana , David, Alexandre , Eguren, Manuel , Birling, Marie-Christine , Urbach, Serge , Hem, Sonia , Déjardin, Jérôme , Malumbres, Marcos , Jay, Philippe , Dulic, Vjekoslav , Lafontaine, Denis Lj , Feil, Robert and Fisher, Daniel
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Antigen Ki-67 is a nuclear protein expressed in proliferating mammalian cells. It is widely used in cancer histopathology but its functions remain unclear. Here, we show that Ki-67 controls heterochromatin organisation. Altering Ki-67 expression levels did not significantly affect cell proliferation in vivo. Ki-67 mutant mice developed normally and...
Alternative Titles
Full title
The cell proliferation antigen Ki-67 organises heterochromatin
Authors, Artists and Contributors
Author / Creator
Mrouj, Karim
Camasses, Alain
Parisis, Nikolaos
Nicolas, Emilien
Llères, David
Gerbe, François
Prieto, Susana
Krasinska, Liliana
David, Alexandre
Eguren, Manuel
Birling, Marie-Christine
Urbach, Serge
Hem, Sonia
Déjardin, Jérôme
Malumbres, Marcos
Jay, Philippe
Dulic, Vjekoslav
Lafontaine, Denis Lj
Feil, Robert
Fisher, Daniel
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c83b0fd6e4ff45c3b6dae215afe87785
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c83b0fd6e4ff45c3b6dae215afe87785
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.13722
