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Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8473773cdfe4e9cbfe7eeeede635aca

Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

About this item

Full title

Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2020-04, Vol.11 (1), p.1970-12, Article 1970

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Succinic acid (SA), a dicarboxylic acid of industrial importance, can be efficiently produced by metabolically engineered
Mannheimia succiniciproducens
. Malate dehydrogenase (MDH) is one of the key enzymes for SA production, but has not been well characterized. Here we report biochemical and structural analyses of various MDHs and developmen...

Alternative Titles

Full title

Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c8473773cdfe4e9cbfe7eeeede635aca

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8473773cdfe4e9cbfe7eeeede635aca

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-15839-z

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