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Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8529b07c7914a5394f32d161d299fea

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

About this item

Full title

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2023-04, Vol.12

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Microtubules serve as tracks for long-range intracellular trafficking of glucose transporter 4 (GLUT4), but the role of this process in skeletal muscle and insulin resistance is unclear. Here, we used fixed and live-cell imaging to study microtubule-based GLUT4 trafficking in human and mouse muscle fibers and L6 rat muscle cells. We found GLUT4 loc...

Alternative Titles

Full title

Microtubule-mediated GLUT4 trafficking is disrupted in insulin-resistant skeletal muscle

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c8529b07c7914a5394f32d161d299fea

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8529b07c7914a5394f32d161d299fea

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.83338

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