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Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the op...

Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the op...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c86571642f3042ac94a9ffd97f1904dc

Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open‐source R package mapbayr

About this item

Full title

Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open‐source R package mapbayr

Publisher

United States: John Wiley & Sons, Inc

Journal title

CPT: Pharmacometrics & Systems Pharmacology, 2021-10, Vol.10 (10), p.1208-1220

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Pharmacokinetic (PK) parameter estimation is a critical and complex step in the model‐informed precision dosing (MIPD) approach. The mapbayr package was developed to perform maximum a posteriori Bayesian estimation (MAP‐BE) in R from any population PK model coded in mrgsolve. The performances of mapbayr were assessed using two approaches. First, “t...

Alternative Titles

Full title

Easy and reliable maximum a posteriori Bayesian estimation of pharmacokinetic parameters with the open‐source R package mapbayr

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c86571642f3042ac94a9ffd97f1904dc

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c86571642f3042ac94a9ffd97f1904dc

Other Identifiers

ISSN

2163-8306

E-ISSN

2163-8306

DOI

10.1002/psp4.12689

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