Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct sin...
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification
About this item
Full title
Author / Creator
Zhang, Yuhang , Du, Jingyi , Liu, Xian , Shang, Fei , Deng, Yunxin , Ye, Jiaqing , Wang, Yukai , Yan, Jie , Chen, Hu , Yu, Miao and Le, Shimin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
α
-Actinins play crucial roles in cytoskeletal mechanobiology by acting as force-bearing structural modules that orchestrate and sustain the cytoskeletal framework, serving as pivotal hubs for diverse mechanosensing proteins. The mechanical stability of
α
-actinin dimer, a determinant of its functional state, remains largely unexplored. He...
Alternative Titles
Full title
Multi-domain interaction mediated strength-building in human α-actinin dimers unveiled by direct single-molecule quantification
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c8a32eabd27f41f18dcd484f7f526eae
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8a32eabd27f41f18dcd484f7f526eae
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-50430-w
