i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations
i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations
About this item
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Author / Creator
Jiang, Junfeng , Chen, Yuanyuan , Zhang, Li , Jin, Qishu , Wang, Liujun , Xu, Sha , Chen, Kexin , Li, Li , Zeng, Tao , Fan, Xingfei , Liu, Tingting , Li, Jiaxi , Wang, Jinjiang , Han, Chaofeng , Gao, Fu , Yang, Yanyong and Wang, Yue
Publisher
London: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
London: BioMed Central Ltd
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Scope and Contents
Contents
Developing a strategy to specifically kill cancer cells without inducing obvious damage to normal cells may be of great clinical significance for cancer treatment. In the present study, we developed a new precise personalized strategy named "i-CRISPR" for cancer treatment through adding DNA damage repair inhibitors(i) and inducing cancer cell-speci...
Alternative Titles
Full title
i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_c8c503ef40b04102b7fbc348c1cb9d7a
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8c503ef40b04102b7fbc348c1cb9d7a
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-022-01612-x
