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Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal c...

Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8cd6bf6609248f79a02e8de99757ec0

Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin–granzyme pathway

About this item

Full title

Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin–granzyme pathway

Publisher

United States: John Wiley & Sons, Inc

Journal title

Molecular oncology, 2021-12, Vol.15 (12), p.3385-3403

Language

English

Formats

Publication information

Publisher

United States: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Invariant natural killer T (iNKT) cells are lipid‐specific T lymphocytes endowed with cytotoxic activities and are thus considered important in antitumor immunity. While several studies have demonstrated iNKT cell cytotoxicity against different tumors, very little is known about their cell‐killing activities in human colorectal cancer (CRC). Our ai...

Alternative Titles

Full title

Human intestinal and circulating invariant natural killer T cells are cytotoxic against colorectal cancer cells via the perforin–granzyme pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_c8cd6bf6609248f79a02e8de99757ec0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8cd6bf6609248f79a02e8de99757ec0

Other Identifiers

ISSN

1574-7891

E-ISSN

1878-0261

DOI

10.1002/1878-0261.13104

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