Senescent cell turnover slows with age providing an explanation for the Gompertz law
Senescent cell turnover slows with age providing an explanation for the Gompertz law
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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A causal factor in mammalian aging is the accumulation of senescent cells (SnCs). SnCs cause chronic inflammation, and removing SnCs decelerates aging in mice. Despite their importance, turnover rates of SnCs are unknown, and their connection to aging dynamics is unclear. Here we use longitudinal SnC measurements and induction experiments to show t...
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Senescent cell turnover slows with age providing an explanation for the Gompertz law
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TN_cdi_doaj_primary_oai_doaj_org_article_c8d1148874e54b7f9c4cf46bb629afe1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_c8d1148874e54b7f9c4cf46bb629afe1
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-13192-4
